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Thioredoxin domain-containing protein 5

WebSep 28, 2024 · As a critical member of the PDI family, thioredoxin domain containing protein 5 (TXNDC5) assists the folding of newly synthesized peptides to their mature form through series of disulfide bond exchange reactions. Interestingly, TXNDC5 is frequently found overexpressed in specimens of many human diseases including various types of cancer. WebTwo novel proteins, mimecan and thioredoxin domain–containing protein 5 (TXNDC5), were further validated by Western blot in 8 colorectal adenomas and 19 cancers that were matched with normal mucosa. All adenoma and cancer tissues did not express mimecan, but all normal mucosa did (P < 0.01).

Txndc5 MGI Mouse Gene Detail - MGI:2145316 - thioredoxin domain …

WebMar 29, 2024 · Overactivated osteoclasts lead to many bone diseases, including osteoporosis and rheumatoid arthritis. The p38 MAPK (p38) is an essential regulator of the receptor activator of nuclear factor-κB ligand (RANKL)-mediated osteoclastogenesis and bone loss. We previously reported TAT conjugated thioredoxin-interacting protein … Web2. TXNIP. Thioredoxin-interacting protein (TXNIP), also known as vitamin D upregulated protein-1 (VDUP-1) or thioredoxin-binding protein-2 (TBP-2), is a multifunctional protein that is essential for many cellular processes such as metabolic activities, growth, division, and cell death [].It was initially believed that TXNIP was restricted only to the cytoplasm. cryptography foundation https://t-dressler.com

P593Endoplasmic reticulum protein thioredoxin domain containing 5 …

WebPossesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide-isomerase deficiency in yeast (By similarity). This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The … WebDec 1, 2024 · As a critical member of the PDI family, thioredoxin domain containing protein 5 (TXNDC5) assists the folding of newly synthesized peptides to their mature form … WebFeb 10, 2024 · Thioredoxin (Trx) proteins, a class of conserved, thermostable, acidic small proteins [] that are widely found in chloroplasts, yeast, animals, and plants [2,3,4], share the highly conserved active site core sequence Trp-Cys-Gly-Pro-Cys (WCXXC).Within this core sequence, two Cys residues confer unique biological properties to Trx proteins by … dust chemical

The role and mechanism of TXNDC5 in diseases European Journ…

Category:Thioredoxin domain - Wikipedia

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Thioredoxin domain-containing protein 5

A critical role of the thioredoxin domain containing protein 5 …

WebMay 31, 2024 · Through MS analysis, we determined that Srx forms a complex with the ER-resident protein thioredoxin domain-containing protein 5 (TXNDC5). Using reciprocal co-immunoprecipitation, immunofluorescence imaging, subcellular fractionation, and domain-mapping assays with site-specific mutagenesis and purified recombinant proteins, we … WebRecombinant Human Thioredoxin domain-containing protein 5(TXNDC5) ( Yeast-CSB-YP847679HU Baculovirus-CSB-BP847679HU Mammalian cell-CSB-MP847679HU In Vivo Biotinylation in E.coli-CSB-EP847679HU-B ) See all products about TXNDC5 >> Customer Reviews and Q&A Customer Reviews. There are currently no reviews for this product. ...

Thioredoxin domain-containing protein 5

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Web(thioredoxin domain containing 5), a cardiac fibroblast (CF)–enriched endoplasmic reticulum protein, as a potential novel mediator of cardiac fibrosis, and we completed experiments to test this hypothesis directly. Objective: The objective of this study was to determine the functional role of TXNDC5 in the pathogenesis of cardiac fibrosis. WebTXNDC5, thioredoxin domain containing 5 Vertebrate Orthologs 3 Vertebrate Orthology Source. Alliance of Genome Resources. Human Ortholog ... PR:000016863 thioredoxin domain-containing protein 5 (term hierarchy) EC. 1.8.4.-, 5.3.4.1. InterPro Domains. IPR005788 Disulphide isomerase.

WebTxndc5. Name. thioredoxin domain containing 5. Synonyms. ERp46, PC-TRP. Feature Type. protein coding gene. IDs. MGI:2145316. WebDec 4, 2024 · thioredoxin domain-containing protein 17, 14 kDa thioredoxin-related protein, protein 42-9-9, testicular tissue protein Li 214, thioredoxin (Trx)-related protein, 14 kDa, thioredoxin-like 5, thioredoxin-like protein 5. GeneRIFs: Gene References Into Functions. Cellular S-denitrosylases: Potential role and interplay of Thioredoxin, TRP14, and ...

WebNov 14, 2024 · Amplified cDNA was sub-cloned in pET32a containing thioredoxin (Trx) and histidine (His) tags (Novagen). The resultant clone, the Trx-Gγ3 domain vector, was transformed in T7 Express lysY / I q E. coli (New England Biolabs), and the recombinant protein was synthesized and designated as the Trx-Gγ3 domain protein. The cDNA … WebRelevant books, articles, theses on the topic 'Thioredoxin domain containing protein 5.' Scholarly sources with full text pdf download. Related research topic ideas.

WebJun 1, 2001 · Thioredoxin domain-containing protein 17 Alternative names 14 kDa thioredoxin-related protein ( TRP14) Protein 42-9-9 Thioredoxin-like protein 5 Gene …

WebProteomics and gene expression analyses of squalene-supplemented mice identify microsomal thioredoxin domain-containing protein 5 changes associated with hepatic … dust child groomingWebSep 19, 2024 · disintegrin and metalloproteinase domain-containing protein 10: 3.24: 1.7: 21.76: 2.75 × 10 −3: 0.028: yes ... MLRs were set up as described in figure 5 and in the presence of the thioredoxin inhibitor PX-12, and analysed by flow cytometry at the time points indicated. cryptography forouzan pptWebAug 28, 2024 · Endoplasmic reticulum protein thioredoxin domain containing 5 (TXNDC5) is a novel mediator of endothelial dysfunction and atherosclerosis, European Heart Journal, Volume 39, ... (HAECs) stimulated with atherogenic disturbed flow, we identified thioredoxin domain containing 5 (TXNDC5), an endoplasmic reticulum (ER) protein with the enzyme ... dust child highway to heavenWebProteomics and gene expression analyses of squalene-supplemented mice identify microsomal thioredoxin domain-containing protein 5 changes associated with hepatic steatosis Author links open overlay panel Adela Ramírez-Torres a , Sílvia Barceló-Batllori b , Roberto Martínez-Beamonte a e , María A. Navarro c e , Joaquín C. Surra a e ... cryptography from learning parity with noiseWebMay 31, 2024 · Through MS analysis, we determined that Srx forms a complex with the ER-resident protein thioredoxin domain-containing protein 5 (TXNDC5). Using reciprocal co … dust child meaningWebSep 28, 2024 · DOI: 10.1016/j.gendis.2024.09.003 Corpus ID: 57012805; A critical role of the thioredoxin domain containing protein 5 (TXNDC5) in redox homeostasis and cancer development @article{Chawsheen2024ACR, title={A critical role of the thioredoxin domain containing protein 5 (TXNDC5) in redox homeostasis and cancer development}, … cryptography frameworkWebMar 29, 2024 · thioredoxin domain containing 15 provided by HGNC Primary source HGNC:HGNC:20652 MIM:617778; AllianceGenome:HGNC:20652 Gene type protein coding … cryptography from anonymity