WebMay 29, 2024 · To elucidate the pharmacophore of echinocystic acid (EA), an oleanane-type triterpene displaying substantial inhibitory activity on HCV entry, two microbial strains, Rhizopus chinensis CICC 3043 ... WebJan 6, 2015 · After introducing this enzyme together with oxidosqualene cyclase, a P450 enzyme that catalyzes a multistep oxidation at C-28, and glycosyltransferase from other plant species into S. cerevisiae, a yeast cell factory for production of oleanane-type triterpene saponins of 3-O-Glc-echinocystic acid was obtained (Moses et al., 2014).
Echinocyte - Wikipedia
WebBackground: Echinocystic acid (EA), a natural extract from plants of Gleditsia sinensis Lam, exhibits anti-inflammatory, antioxidant and analgesic activities in different diseases. WebJun 17, 2002 · The constituents of the polar fraction of the roots of C. lanceolata were studied and six new triterpene saponins, lancemasides B, C, D, L, and G were identified, thought to be oleanan-type bisdesmoside with sugars at C-3 and C-28 and echinocystic acid as an aglycone. Expand fanatic\u0027s x8
Effects of Echinocystic Acid on Atopic Dermatitis and …
WebAug 28, 2015 · Echinocystic acid (EA) is a natural triterpone enriched in various herbs and has been used for medicinal purposes in China. In the present study, we systematically … WebSep 3, 2008 · Activity-guided fractionation led to the isolation of five oleanane-type triterpenoids, echinocystic acid (1), ... Among the five echinocystic acid derivatives isolated, echinocystic acid (1) and eclalbasaponin II (2) significantly inhibited the proliferation of HSCs in dose- and time-dependent manners. Our present study also … WebOct 15, 2024 · Echinocystic acid (EA) was found to possess antiviral, anti-inflammatory and antioxidation activities. A recent study showed the antiapoptotic effects of EA on acute myocardial infarction.In this study, we demonstrated the potential neuroprotective effects of EA on cerebral ischemia/reperfusion (I/R) injury in mice. Intraperitoneal injection of EA 1 … fanatic\\u0027s wz